01 - Preheat oven to 400°F. Line a baking sheet with parchment paper or lightly grease it.
02 - Combine smoked paprika, garlic powder, onion powder, dried thyme, dried oregano, cayenne pepper, salt, and black pepper in a small bowl.
03 - Pat salmon fillets dry with paper towels. Brush both sides lightly with olive oil. Rub the Cajun spice mix evenly over the salmon fillets.
04 - Place salmon fillets skin-side down on the prepared baking sheet.
05 - Whisk together honey, lemon juice, and melted butter in a separate bowl to create the glaze.
06 - Spoon half the honey glaze evenly over the top of the spiced salmon fillets.
07 - Bake for 10-12 minutes, or until the salmon is almost cooked through and flakes easily with a fork.
08 - Remove from oven, brush with the remaining honey glaze, and broil for 1-2 minutes for a caramelized finish.
09 - Garnish with chopped parsley and serve with lemon wedges if desired.